Superparamagnetic iron oxide nanoparticles for MR imaging and therapy: design considerations and clinical applications

Highlights • Surface engineering of SPION determines their in vivo performance. • Targeting mechanisms of SPION imaging are summarized. • Clinical trial information related to SPION on Clinicaltrials.gov is analyzed.

Saved in:
Bibliographic Details
Published in:Current opinion in pharmacology 2014-10, Vol.18, p.18-27
Main Authors: Jin, Rongrong, Lin, Bingbing, Li, Danyang, Ai, Hua
Format: Article
Language:English
Subjects:
Animals
Contrast Media - therapeutic use
Drug Design
Ferric Compounds - pharmacokinetics
Ferric Compounds - therapeutic use
Humans
Internal Medicine
Magnetic Resonance Imaging
Medical Education
Metal Nanoparticles - therapeutic use
Surface Properties
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • Surface engineering of SPION determines their in vivo performance. • Targeting mechanisms of SPION imaging are summarized. • Clinical trial information related to SPION on Clinicaltrials.gov is analyzed.
ISSN:1471-4892
1471-4973
DOI:10.1016/j.coph.2014.08.002