The choice of mammalian cell host and possibilities for glycosylation engineering

Graphical abstract CHO cells produce antibodies with specific glycan profiles.

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Bibliographic Details
Published in:Current opinion in biotechnology 2014-12, Vol.30, p.107-112
Main Authors: Butler, Michael, Spearman, Maureen
Format: Article
Language:English
Subjects:
Animals
Cell Culture Techniques
Cell Line
CHO Cells
Cricetulus
Glycosylation
Internal Medicine
Mammals
Polysaccharides - chemistry
Polysaccharides - metabolism
Recombinant Proteins - chemistry
Recombinant Proteins - metabolism
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Description
Summary:Graphical abstract CHO cells produce antibodies with specific glycan profiles.
ISSN:0958-1669
1879-0429
DOI:10.1016/j.copbio.2014.06.010