25-hydroxy vitamin D and its relationship with clinical and laboratory parameters in patients with rheumatoid arthritis

• Published in: Clinical rheumatology 2015-02, Vol.34 (2), p.353-357
• Main Authors: Abourazzak, F. E., Talbi, S., Aradoini, N., Berrada, K., Keita, S., Hazry, T.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid - blood; Arthritis, Rheumatoid - complications; Brief Report; Female; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Prevalence; Rheumatology; Severity of Illness Index; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D Deficiency - blood; Vitamin D Deficiency - complications; Vitamin D Deficiency - epidemiology; Young Adult
• ISSN: 0770-3198; 1434-9949
• DOI: 10.1007/s10067-014-2713-0

The objective of this study is to evaluate the prevalence of vitamin D insufficiency in patients with rheumatoid arthritis (RA) and its association with disease activity, severity and physical disability. We included patients with rheumatoid arthritis followed in Rheumatology Department of Hassan II University Hospital, Fez, Morocco. Patients suffering from liver and kidney insufficiency and those who had received vitamin D in the previous 12 months have been excluded. Statistical analysis was done using SPSS v 18. A bivariate analysis and logistic regression were used to identify factors associated with vitamin D deficiency. One hundred seventy patients were included with a mean age of 50 ± 12.1 [17–83] years, and a female predominance (88.1 %). All of our patients had hypovitaminosis D. The prevalence of 25(OH)-D insufficiency and deficiency was 64.5 and 35.5 % successively. In unadjusted analysis, vitamin D concentration was inversely associated with pain visual analog scale VAS score ( p