Elevated Baseline Cardiac Troponin Levels in the Elderly – Another Variable to Consider?

Aims This study aimed to determine the frequency of baseline high-sensitivity troponin T (hs-TnT) elevation in different age groups presenting to the Emergency Department without acute coronary syndromes (ACS) or other acute illnesses known to cause to troponin elevation. We additionally sought to d...

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Bibliographic Details
Published in:Heart, lung & circulation lung & circulation, 2015-02, Vol.24 (2), p.142-148
Main Authors: Webb, Ian G, Yam, S.T, Cooke, Russel, Aitken, Andrew, Larsen, Peter D, Harding, Scott A
Format: Article
Language:English
Subjects:
Acute Coronary Syndrome - blood
Adult
Aged
Aged, 80 and over
Aging - blood
Cardiovascular
Chest pain
Diagnosis
Elderly
Female
Humans
Male
Middle Aged
Myocardial infarction
Myocardial Infarction - blood
Retrospective Studies
Sex Factors
Troponin
Troponin T - blood
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Summary:Aims This study aimed to determine the frequency of baseline high-sensitivity troponin T (hs-TnT) elevation in different age groups presenting to the Emergency Department without acute coronary syndromes (ACS) or other acute illnesses known to cause to troponin elevation. We additionally sought to determine whether the relationship between age and hs-TnT was independent of co-morbidities. Methods We retrospectively analysed data on all patients presenting to the Emergency Department (ED) between November 2010 and June 2011 in whom hs-TnT was measured. Patients presenting with acute coronary syndromes (ACS) or other acute illness known to elevate hs-TnT levels were excluded. Demographics, clinical characteristics and diagnosis were recorded, together with hs-TnT assay results. Results Of 3219 patients with hs-TnT testing in the ED during the study period, 526 with proven/suspected ACS and 1376 with other acute medical conditions known to elevate troponin concentrations were excluded. The percentage of patients with hs-TnT concentrations elevated above the upper reference limit (>14ng/L) increased with age:
ISSN:1443-9506
1444-2892
DOI:10.1016/j.hlc.2014.07.071