Moyamoya in a patient with Sneddon's syndrome

Thickened wall and endothelial swelling of the superficial dermal capillaries were found at the skin biopsy histological examination, supporting the SNS diagnosis (Fig. 2B). Because of stroke occurrence while on antiplatelet therapy, anticoagulation was started, but 3 months after discharge the pati...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2015-02, Vol.129, p.34-36
Main Authors: Fierini, Fabio, Barilaro, Alessandro, Giambene, Barbara, Carlucci, Giovanna, Grandi, Vieri, Maio, Vincenza, Pantoni, Leonardo
Format: Article
Language:English
Subjects:
Adult
Anticoagulants
Brain - blood supply
Brain - pathology
Diagnosis, Differential
Female
Humans
Leg - pathology
Livedo racemosa
Medical imaging
Moyamoya
Moyamoya Disease - complications
Moyamoya Disease - diagnosis
Moyamoya Disease - pathology
Neurology
Neurosurgery
Patients
Skin
Skin - pathology
Skin biopsy
Sneddon Syndrome - complications
Sneddon Syndrome - diagnosis
Sneddon Syndrome - pathology
Sneddon's syndrome
Therapy
Veins & arteries
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Summary:Thickened wall and endothelial swelling of the superficial dermal capillaries were found at the skin biopsy histological examination, supporting the SNS diagnosis (Fig. 2B). Because of stroke occurrence while on antiplatelet therapy, anticoagulation was started, but 3 months after discharge the patient suffered from an acute onset episode of weakness in her right arm. An ischemic lesion was detected by diffusion-weighted MRI in the left precentral gyrus. Because a brain CT perfusion detected a widespread subcortical hypoperfusion especially pronounced in the border-zone territories, a hemodynamic mechanism was supposed for the recurrent strokes.
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2014.12.001