Relationship between time to invasive assessment and clinical outcomes of patients undergoing an early invasive strategy after fibrinolysis for ST-segment elevation myocardial infarction: a patient-level analysis of the randomized early routine invasive clinical trials

This study investigated the relationship between time to invasive assessment and outcomes among ST-segment elevation myocardial infarction patients randomized to early angiography after fibrinolysis. The optimal timing of coronary angiography after fibrinolysis and the association with clinical outc...

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Bibliographic Details
Published in:JACC. Cardiovascular interventions 2015-01, Vol.8 (1 Pt B), p.166-174
Main Authors: Madan, Mina, Halvorsen, Sigrun, Di Mario, Carlo, Tan, Mary, Westerhout, Cynthia M, Cantor, Warren J, Le May, Michel R, Borgia, Francesco, Piscione, Federico, Scheller, Bruno, Armstrong, Paul W, Fernandez-Aviles, Francisco, Sanchez, Pedro L, Graham, John J, Yan, Andrew T, Goodman, Shaun G
Format: Article
Language:English
Subjects:
Aged
Chi-Square Distribution
Coronary Angiography
Databases, Factual
Female
Fibrinolytic Agents - administration & dosage
Fibrinolytic Agents - adverse effects
Hemorrhage - chemically induced
Humans
Male
Markov Chains
Middle Aged
Monte Carlo Method
Multivariate Analysis
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - drug therapy
Myocardial Infarction - mortality
Predictive Value of Tests
Proportional Hazards Models
Randomized Controlled Trials as Topic
Recurrence
Retrospective Studies
Risk Factors
Thrombolytic Therapy - adverse effects
Thrombolytic Therapy - mortality
Time Factors
Treatment Outcome
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Description
Summary:This study investigated the relationship between time to invasive assessment and outcomes among ST-segment elevation myocardial infarction patients randomized to early angiography after fibrinolysis. The optimal timing of coronary angiography after fibrinolysis and the association with clinical outcomes is uncertain. Patient-level data from 6 randomized trials, with a median time to angiography
ISSN:1876-7605
DOI:10.1016/j.jcin.2014.09.005