The effect of maternal body condition on in vivo production of zygotes and behavior of delivered offspring in mice

This study investigated the effects of maternal body condition on oocyte quality and zygote production. Additionally, we examined the possible consequences on somatic parameters and behavior of naturally delivered offspring. We used an experimental model based on overfeeding of outbred mice during i...

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Bibliographic Details
Published in:Theriogenology 2015-03, Vol.83 (4), p.577-589
Main Authors: Fabian, Dušan, Kubandová, Janka, Čikoš, Štefan, Burkuš, Ján, Fabianová, Kamila, Račeková, Enikö, Czikková, Soňa, Koppel, Juraj
Format: Article
Language:English
Subjects:
Adipose Tissue - physiology
Animal Feed - analysis
Animals
Behavior, Animal - physiology
Body Composition - physiology
Body Weight
Diet
DNA methylation
Fat deposit
Female
Male
Mice
Mice, Inbred ICR
Offspring behavior
Oocyte
Oocytes - physiology
Overnutrition
Pregnancy
Random Allocation
Zygote
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Summary:This study investigated the effects of maternal body condition on oocyte quality and zygote production. Additionally, we examined the possible consequences on somatic parameters and behavior of naturally delivered offspring. We used an experimental model based on overfeeding of outbred mice during intrauterine and early postnatal development to produce the following four types of females: physiological (7%–8%), slightly increased (8%–11%), highly increased (>11%), and low (
ISSN:0093-691X
1879-3231
DOI:10.1016/j.theriogenology.2014.10.025