Impact of transcatheter aortic valve implantation (TAVI) on pulmonary hyper-tension and clinical outcome in patients with severe aortic valvular stenosis

Background Transcatheter aortic valve implantation (TAVI) is a proven alternative to open heart surgery in elderly patients. Pulmonary hypertension (PH) is known as a significant risk factor in patients with severe aortic stenosis (AS) undergoing surgical aortic valve replacement. However, the progn...

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Bibliographic Details
Published in:Clinical research in cardiology 2015-02, Vol.104 (2), p.164-174
Main Authors: Schewel, Dimitry, Schewel, Jury, Martin, Julia, Voigtländer, Lisa, Frerker, Christian, Wohlmuth, Peter, Thielsen, Thomas, Kuck, Karl-Heinz, Schäfer, Ulrich
Format: Article
Language:English
Subjects:
Age Distribution
Aged
Aged, 80 and over
Aortic Valve Stenosis - mortality
Aortic Valve Stenosis - surgery
Cardiology
Clinical outcomes
Comorbidity
Female
Germany - epidemiology
Humans
Hypertension, Pulmonary - mortality
Hypertension, Pulmonary - surgery
Incidence
Male
Medicine
Medicine & Public Health
Middle Aged
Original Paper
Prognosis
Risk Factors
Sex Distribution
Survival Rate
Transcatheter Aortic Valve Replacement - mortality
Treatment Outcome
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Summary:Background Transcatheter aortic valve implantation (TAVI) is a proven alternative to open heart surgery in elderly patients. Pulmonary hypertension (PH) is known as a significant risk factor in patients with severe aortic stenosis (AS) undergoing surgical aortic valve replacement. However, the prognostic impact of PH in high-risk patients undergoing TAVI is still unknown. The aim of this study was to gain more insight in the clinical outcome and mortality of patients with PH after TAVI. Methods and results Between July 2009 and September 2012, a total of 439 patients were treated by TAVI in conjunction with a complete invasive right heart study at our institution. Patients were divided into two groups with regard to their pulmonary arterial mean pressure (PAMP) before TAVI (A: PAMP 
ISSN:1861-0684
1861-0692
DOI:10.1007/s00392-014-0772-5