Myocardial performance index in fetal anemia

Objective The objective of the study was to examine the correlation between fetal myocardial performance index (MPI) and hemoglobin (Hb) levels. Methods It is a prospective study involving singleton pregnancies at risk of fetal anemia as a result of maternal anti‐D alloimmune disease. Right and left...

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Bibliographic Details
Published in:Prenatal diagnosis 2015-02, Vol.35 (2), p.192-196
Main Authors: de Assunção, Renata Almeida, Liao, Adolfo Wenjaw, de Lourdes Brizot, Maria, Francisco, Rossana Pulcineli Vieira, Zugaib, Marcelo
Format: Article
Language:English
Subjects:
Adult
Anemia - physiopathology
Female
Fetal Diseases - physiopathology
Heart - physiopathology
Humans
Pregnancy
Prospective Studies
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Summary:Objective The objective of the study was to examine the correlation between fetal myocardial performance index (MPI) and hemoglobin (Hb) levels. Methods It is a prospective study involving singleton pregnancies at risk of fetal anemia as a result of maternal anti‐D alloimmune disease. Right and left ventricle (LV) MPIs were evaluated by ultrasound up to 72 h before cordocentesis. Zeta‐score values for fetal MPI and Hb levels were calculated, and correlation was examined with linear regression analysis. Significance level was set as 0.05. Results Fourteen singleton pregnancies underwent 31 cordocentesis procedures at a mean gestation of 28.2 ± 4.1 weeks. Zeta‐score values for LV MPI, isovolumetric relaxation time (IRT), and ejection time (ET) correlated significantly with fetal Hb zeta‐score (LV MPI zeta = 3.816 + 0.336 × Hb zeta, r = 0.59, p 
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.4526