Modulation of swimming behavior in the medicinal leech. 1. Effects of serotonin on the electrical properties of swim-gating cell 204

The effects of serotonin on the electrical properties of swim-gating neurons (cell 204) were examined in leech (Hirudo medicinalis ) nerve cords. Exposure to serotonin decreased the threshold current required to elicit swim episodes by prolonged depolarization of an individual cell 204 in isolated n...

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Bibliographic Details
Published in:Journal of Comparative Physiology, A A, 1993-03, Vol.172 (2), p.223-234
Main Authors: Angstadt, J D, Friesen, W O
Format: Article
Language:English
Subjects:
Freshwater
Hirudo medicinalis
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Summary:The effects of serotonin on the electrical properties of swim-gating neurons (cell 204) were examined in leech (Hirudo medicinalis ) nerve cords. Exposure to serotonin decreased the threshold current required to elicit swim episodes by prolonged depolarization of an individual cell 204 in isolated nerve cords. Serotonin had little effects on the steady-state current-voltage relation of cell 204. The changes suggest that serotonin modulates one or more voltage dependent conductances in cell 204, resulting in a more rapid depolarization and greater firing rate in response to injected currents.
ISSN:0340-7594
DOI:10.1007/BF00189398