Histopathological changes induced by malathion in the liver of a freshwater catfish, Heteropneustes fossilis (Bloch)

Adult female catfish were exposed to a sublethal 1.2 mg per litre concentration of malathion for 24-96 h at pH 7.2-7.4, 20C, and alkalinity of 114 mg calcium carbonate per litre. Sections of liver were fixed and examined by microscopy. Shrinkage of hepatic cells began within 24 h and contracted 30 p...

Full description

Saved in:
Bibliographic Details
Published in:Bulletin of environmental contamination and toxicology 1993-12, Vol.51 (6), p.895-900
Main Authors: Dutta, H.M, Adhikari, S, Singh, N.K, Roy, P.K, Munshi, J.S.D
Format: Article
Language:English
Subjects:
Animals
BAGRE DE AGUA DULCE
Catfishes - physiology
Cell Nucleolus - drug effects
Cell Nucleus - drug effects
Cell Size - drug effects
CELLS
CELLULE
CELULAS
Cytoplasm - drug effects
DURACION
DURATION
DUREE
EFECTOS SECUNDARIOS
EFFET SECONDAIRE
EXPOSURE
Female
FOIE
Freshwater
FRESHWATER CATFISH
HIGADO
HISTOPATHOLOGY
LIVER
Liver - cytology
Liver - drug effects
Liver - ultrastructure
MALATHION
Malathion - toxicity
MALATION
NONTARGET EFFECTS
NONTARGET ORGANISMS
PATHOLOGIE
PATHOLOGY
PATOLOGIA
POISSON CHAT (D'EAU DOUCE)
SIDE EFFECTS
SUBLETHAL EFFECTS
Time Factors
TOXICIDAD
TOXICITE
TOXICITY
Vacuoles - drug effects
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Adult female catfish were exposed to a sublethal 1.2 mg per litre concentration of malathion for 24-96 h at pH 7.2-7.4, 20C, and alkalinity of 114 mg calcium carbonate per litre. Sections of liver were fixed and examined by microscopy. Shrinkage of hepatic cells began within 24 h and contracted 30 per cent in 72 h. After 96 h the cells had regained their original size but extensive damage had occurred, with dilation and vacuolation. The level of malathion clearly caused significant liver damage which could result in death.
ISSN:0007-4861
1432-0800
DOI:10.1007/BF00198287