Outcomes of intraventricular hemorrhage and post-hemorrhagic hydrocephalus in a population-based cohort of very-preterm infants born to residents of Nova Scotia from 1993 to 2010

Background: Intraventicular hemorrhage (IVH) and post-hemorrhagic hydrocephalus (PHH) are common complications of preterm birth. We describe 2-3 year outcomes of IVH, PHH and shunt surgery in a population-based cohort of very-preterm infants (> 19 and < 31 weeks gestational age) with minimal s...

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Bibliographic Details
Published in:Canadian journal of neurological sciences 2014-05, Vol.41 (3), p.S52-S52
Main Authors: Radic, J A, Vincer, M, McNeely, P D
Format: Article
Language:English
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Summary:Background: Intraventicular hemorrhage (IVH) and post-hemorrhagic hydrocephalus (PHH) are common complications of preterm birth. We describe 2-3 year outcomes of IVH, PHH and shunt surgery in a population-based cohort of very-preterm infants (> 19 and < 31 weeks gestational age) with minimal selection bias. Methods: A perinatal database that includes all very-preterm infants born from 1993 onwards to residents of Nova Scotia was screened for successfully resuscitated infants born from January 1, 1993 to December 31, 2010. Univariate/multivariate logistic regression were used to look at the associations between IVH and primary outcome measures ('overall mortality at 1 year after birth', 'any disability'), and secondary outcome measures ('severe disability', 'cerebral palsy (CP)', 'hydrocephalus', 'shunt surgery', 'blindness, 'deafness', 'MDI cognitive testing score') between birth and final follow-up. Results: On univariate analysis, IVH was significantly associated with an increased overall mortality (OR=2.40, p
ISSN:0317-1671