Prediction of presence of kidney disease in a general patient population undergoing intravenous iodinated contrast enhanced computed tomography

Objective To assess which risk factors can be used to reduce superfluous estimated glomerular filtration rate (eGFR) measurements before intravenous contrast medium administration. Methods In consecutive patients, all decreased eGFR risk factors were assessed: diabetes mellitus (DM), history of urol...

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Bibliographic Details
Published in:European radiology 2014-06, Vol.24 (6), p.1266-1275
Main Authors: Moos, Shira I., Stoker, Jaap, Nagan, Gajenthiran, de Weijert, Roderick S., van Vemde, David N.H., Bipat, Shandra
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cardiovascular disease
Computed Tomography
Contrast Media - adverse effects
Creatinine
Diabetes
Diabetes Mellitus - epidemiology
Diagnostic Radiology
Disease prevention
Female
Glomerular Filtration Rate - drug effects
Humans
Hypertension
Hypertension - epidemiology
Imaging
Injections, Intravenous
Internal Medicine
Interventional Radiology
Iodine - adverse effects
Kidney diseases
Kidney Diseases - chemically induced
Kidney Diseases - epidemiology
Male
Medicine
Medicine & Public Health
Middle Aged
Models, Statistical
Neoplasms - epidemiology
Neuroradiology
Patients
Predictive Value of Tests
Prospective Studies
Radiology
Risk Factors
Tomography
Tomography, X-Ray Computed - adverse effects
Tomography, X-Ray Computed - methods
Ultrasound
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Summary:Objective To assess which risk factors can be used to reduce superfluous estimated glomerular filtration rate (eGFR) measurements before intravenous contrast medium administration. Methods In consecutive patients, all decreased eGFR risk factors were assessed: diabetes mellitus (DM), history of urologic/nephrologic disease (HUND), nephrotoxic medication, cardiovascular disease, hypertension, age > 60 years, anaemia, malignancy and multiple myeloma/M. Waldenström. We studied four models: (1) all risk factors, (2) DM, HUND, hypertension, age > 60 years; (3) DM, HUND, cardiovascular disease, hypertension; (4) DM, HUND, age > 75 years and congestive heart failure. For each model, association with eGFR 
ISSN:0938-7994
1432-1084
DOI:10.1007/s00330-014-3149-2