Pons herniation into skull base after cabergoline therapy of giant prolactinoma

Introduction Pons herniation after cabergoline therapy for giant prolactinoma is a complication not documented in literature. Case report We report a medium aged patient who developed secondary hemiparesis after 18 months of medical treatment. MRI revealed pons herniation into the clivus. There was...

Full description

Saved in:
Bibliographic Details
Published in:Pituitary 2015-02, Vol.18 (1), p.68-71
Main Authors: Moles Herbera, Jesús, Rivero Celada, David, Montejo Gañan, Inmaculada, Fustero de Miguel, David, Fuentes Uliaque, Carlos, Vela Marín, Ana Carmen
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Endocrinology
Ergolines - therapeutic use
Human Physiology
Humans
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Middle Aged
Pituitary Neoplasms - drug therapy
Pituitary Neoplasms - pathology
Pons - pathology
Prolactinoma - drug therapy
Prolactinoma - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction Pons herniation after cabergoline therapy for giant prolactinoma is a complication not documented in literature. Case report We report a medium aged patient who developed secondary hemiparesis after 18 months of medical treatment. MRI revealed pons herniation into the clivus. There was improvement with conservative treatment. Secuencial MRIs are presented showing the tumor at the moment of the diagnosis, tumor shrinkage and pons herniation. Discussion Some studies have shown that a significant and rapid tumor shrinkage resulting from treatment with cabergoline can occur and it is thought that some complications are related with this tumor regression, as in the presented case.
ISSN:1386-341X
1573-7403
DOI:10.1007/s11102-014-0558-9