An Unusual Exposure to Methyl Bromide Leading to Fatality

• Published in: Clinical toxicology (Philadelphia, Pa.) Pa.), 1998, Vol.36 (4), p.353-357
• Main Authors: Horowitz, B. Zane, Albertson, Timothy E., O'malley, Michael, Swenson, Emilie J.
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Fatal Outcome; Female; Fumigation - adverse effects; Humans; Hydrocarbons, Brominated - analysis; Hydrocarbons, Brominated - poisoning; Medical sciences; Multiple Organ Failure - chemically induced; Pesticides, fertilizers and other agrochemicals toxicology; Seizures - chemically induced; Toxicology
• ISSN: 1556-3650; 0731-3810; 1556-9519; 1097-9875
• DOI: 10.3109/15563659809028032

Abstract Introduction; Methyl bromide has been responsible for deaths that usually occur from its accidental inhalation during fumigation. Case Report; We report an accidental fatality that occurred after methyl bromide seeped through underground conduits from a fumigated building to an adjacent guest house on the same property. The patient developed refractory seizures, intermittent fever, and multiorgan system failure before dying 19 days after exposure. The initial serum bromide was 27 mg/dL. Postmortem analysis detected methyl bromide concentrations of 2.9 mg/dL in the blood, 1.7 mg/dL in the bile, 24 μg/g in the liver, and 28 μg/g in the adipose tissue. Conclusion; Methyl bromide, although applied under acceptable safety standards, led to the inadvertent death of a young woman. Extreme care must be used when fumigating to insure no unsuspected seepage routes exist.