Manually controlled targeted prostate biopsy with real-time fusion imaging of multiparametric magnetic resonance imaging and transrectal ultrasound: An early experience

• Published in: International journal of urology 2015-02, Vol.22 (2), p.173-178
• Main Authors: Shoji, Sunao, Hiraiwa, Shinichiro, Endo, Jun, Hashida, Kazunobu, Tomonaga, Tetsuro, Nakano, Mayura, Sugiyama, Tomoko, Tajiri, Takuma, Terachi, Toshiro, Uchida, Toyoaki
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Endosonography - methods; fusion image; Humans; Image-Guided Biopsy - methods; magnetic resonance imaging; Magnetic Resonance Imaging - methods; Male; Middle Aged; Preoperative Care - methods; Prospective Studies; Prostate - diagnostic imaging; Prostate - pathology; prostate cancer; Prostatectomy; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - surgery; Rectum; Reproducibility of Results; targeted biopsy; Time Factors; transrectal ultrasound
• ISSN: 0919-8172; 1442-2042
• DOI: 10.1111/iju.12643

Objectives To report our early experience with manually controlled targeted biopsy with real‐time multiparametric magnetic resonance imaging and transrectal ultrasound fusion images for the diagnosis of prostate cancer. Methods A total of 20 consecutive patients suspicious of prostate cancer at the multiparametric magnetic resonance imaging scan were recruited prospectively. Targeted biopsies were carried out for each cancer‐suspicious lesion, and 12 systematic biopsies using the BioJet system. Pathological findings of targeted and systematic biopsies were analyzed. Results The median age of the patients was 70 years (range 52–83 years). The median preoperative prostate‐specific antigen value was 7.4 ng/mL (range 3.54–19.9 ng/mL). Median preoperative prostate volume was 38 mL (range 24–68 mL). The number of cancer‐detected cases was 14 (70%). The median Gleason score was 6.5 (range 6–8). Cancer‐detected rates of the systematic and targeted biopsy cores were 6.7 and 31.8%, respectively (P