Age-related and historical changes in the clinical characteristics of sarcoidosis in Japan

Summary Background National surveys conducted in Japan between 1960 and 2004 suggest a gradually increasing incidence of sarcoidosis in women >50 years old with increased involvement of the eye, skin, and heart. However, whether this involvement is due to the increased age at diagnosis is still u...

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Bibliographic Details
Published in:Respiratory medicine 2015-02, Vol.109 (2), p.272-278
Main Authors: Sawahata, Michiru, Sugiyama, Yukihiko, Nakamura, Yosikazu, Nakayama, Masayuki, Mato, Naoko, Yamasawa, Hideaki, Bando, Masashi
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Age Distribution
Age Factors
Aged
Biopsy
Child
Epidemiology
Female
Hospitals
Humans
Incidence
Japan - epidemiology
Laboratories
Liver
Male
Medical imaging
Middle Aged
Pulmonary/Respiratory
Race
Radiography
Retrospective Studies
Risk Factors
Sarcoidosis
Sarcoidosis - epidemiology
Sarcoidosis - pathology
Sex
Women
Young Adult
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Summary:Summary Background National surveys conducted in Japan between 1960 and 2004 suggest a gradually increasing incidence of sarcoidosis in women >50 years old with increased involvement of the eye, skin, and heart. However, whether this involvement is due to the increased age at diagnosis is still unclear. We aimed here to identify the age-related differences in organ involvement in sarcoidosis in Japan, as well as the historical changes in clinical characteristics and the age-specific distribution of cases at diagnosis. Methods We reviewed 588 consecutive Japanese patients newly diagnosed with sarcoidosis between 1974 and 2012 at Jichi Medical University Hospital. We compared organ involvement between subgroups differentiated by sex and age (
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2014.12.012