Factors affecting blood pressure profile in pre and postmenopausal women with obstructive sleep apnea hypopnea syndrome

Purpose Obstructive sleep apnea hypopnea syndrome (OSAHS) is an independent risk factor for development of hypertension. Epidemiological surveys have found that risk of cardiovascular diseases increased in postmenopausal women. However, it is not well known about the profiles of hypertension of wome...

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Bibliographic Details
Published in:Sleep & breathing 2015-03, Vol.19 (1), p.169-174
Main Authors: Xu, Hua Jun, Lan, Xiao Fei, Li, Qing Yun, Zhou, Li Na, Zhang, Xiu Juan, Guo, Qian, Ni, Jin Hua, Cao, Bei
Format: Article
Language:English
Subjects:
Adult
Blood Pressure - physiology
Body Mass Index
Cross-Sectional Studies
Dentistry
Female
Humans
Hypertension
Hypertension - diagnosis
Hypertension - epidemiology
Hypertension - physiopathology
Internal Medicine
Medicine
Medicine & Public Health
Menopause
Middle Aged
Neurology
Original Article
Otorhinolaryngology
Pediatrics
Pneumology/Respiratory System
Polysomnography
Postmenopause - physiology
Premenopause - physiology
Risk Factors
Sleep apnea
Sleep Apnea, Obstructive - diagnosis
Sleep Apnea, Obstructive - epidemiology
Sleep Apnea, Obstructive - physiopathology
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Summary:Purpose Obstructive sleep apnea hypopnea syndrome (OSAHS) is an independent risk factor for development of hypertension. Epidemiological surveys have found that risk of cardiovascular diseases increased in postmenopausal women. However, it is not well known about the profiles of hypertension of women with OSAHS in their different reproductive stages. This study aimed to investigate the difference of blood pressure profile between pre and postmenopausal women with OSAHS. Methods Women who were tested by polysomnography (PSG) ( n  = 207) in Ruijin Hospital were recruited in the study. The subjects were divided into two groups of premenopausal women (24 with and 30 without OSAHS), and two groups of postmenopausal women (116 with and 37 without OSAHS). Among the groups, the differences of demographic and PSG variables were compared. The factors influencing blood pressure were further studied. Results The prevalence of hypertension (56.9 %) in postmenopausal OSAHS patients was higher than the other three groups. Among OSAHS patients, both average systolic blood pressure (SBP) and diastolic blood pressure (DBP) of postmenopausal women were higher than those of premenopausal ones [(129.9 ± 16.16 mmHg vs. 123.7 ± 18.89), (84.96 ± 9.88 mmHg vs. 78.81 ± 10.34), P  = 0.05, P  
ISSN:1520-9512
1522-1709
DOI:10.1007/s11325-014-0983-z