Clinical and epidemiological analysis of keloids in Chinese patients

Keloids are common abnormally raised fibroproliferative lesions that can occur following even minor cutaneous trauma. There are limited data on Chinese patients with keloids, and the purpose of our study was to investigate the clinical and epidemiological features of keloids in Chinese patients. Ass...

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Bibliographic Details
Published in:Archives of Dermatological Research 2015-03, Vol.307 (2), p.109-114
Main Authors: Lu, Wen-sheng, Zheng, Xiao-dong, Yao, Xiu-hua, Zhang, Lan-fang
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Age of Onset
Aged
Asian Continental Ancestry Group - ethnology
Child
Child, Preschool
China - epidemiology
Dermatology
Female
Humans
Infant
Infant, Newborn
Keloid - diagnosis
Keloid - ethnology
Keloid - genetics
Male
Medicine
Medicine & Public Health
Middle Aged
Original Paper
Sex Distribution
Surveys and Questionnaires
Young Adult
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Summary:Keloids are common abnormally raised fibroproliferative lesions that can occur following even minor cutaneous trauma. There are limited data on Chinese patients with keloids, and the purpose of our study was to investigate the clinical and epidemiological features of keloids in Chinese patients. Assessment was performed by unified, designed questionnaires. A total of 715 patients were enrolled and statistical analysis and heritability were performed using EPI INFO 6.0, SPSS13.0 and Falconer’s method. Keloids occurred typically between the ages of 10 and 30 years, and the mean age of initial onset was 21.14 ± 13.45 years in females and 22.55 ± 11.36 years in males. The difference in the mean age of onset was not significant between males and females ( p  > 0.05). A greater severity of keloids was observed in the positive history family group than in the negative history family group, and this difference was statistically significant ( χ 2  = 10.889, p  
ISSN:0340-3696
1432-069X
DOI:10.1007/s00403-014-1507-1