Human amniotic membrane-derived stromal cells (hAMSC) interact depending on breast cancer cell type through secreted molecules

Highlights • Human amniotic membrane-derived stromal cells secreted various cytokines. • Breast cancer cells exposed to hAMSC-CM showed increased proliferation and migration. • Responses of breast cancer cells on hAMSC-CM were different depending on cell type.

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Bibliographic Details
Published in:Tissue & cell 2015-02, Vol.47 (1), p.10-16
Main Authors: Kim, Sun-Hee, Bang, So Hee, Kang, So Yeong, Park, Ki Dae, Eom, Jun Ho, Oh, Il Ung, Yoo, Si Hyung, Kim, Chan-Wha, Baek, Sun Young
Format: Article
Language:English
Subjects:
Advanced Basic Science
Amnion - cytology
Amnion - metabolism
Amniotic membrane
Breast Neoplasms - genetics
Breast Neoplasms - pathology
Cell Movement - genetics
Cell Proliferation - genetics
Cell- and Tissue-Based Therapy - adverse effects
Chemokine CCL2 - biosynthesis
Chemokine CXCL1 - biosynthesis
Female
Gene Expression Regulation, Neoplastic
Humans
Interleukin-8 - biosynthesis
MCF-7
MCF-7 Cells
MDA-MB-231
Secretion
Stromal Cells
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Description
Summary:Highlights • Human amniotic membrane-derived stromal cells secreted various cytokines. • Breast cancer cells exposed to hAMSC-CM showed increased proliferation and migration. • Responses of breast cancer cells on hAMSC-CM were different depending on cell type.
ISSN:0040-8166
1532-3072
DOI:10.1016/j.tice.2014.10.003