A meta-analysis of the effects of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers on insulin sensitivity in hypertensive patients without diabetes

Highlights • We collect the data of insulin sensitivity with hypertensive patients. • A total of 203 cases of patients involved in 4 clinical studies were included. • ACEI is more effective than ARB on improve insulin sensitivity. • ACEI and ARB do not show significant differences with FPG, FPI and...

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Bibliographic Details
Published in:Diabetes research and clinical practice 2015-03, Vol.107 (3), p.415-423
Main Authors: Yang, Yue, Wei, Ri-bao, Wang, Zi-cheng, Wang, Na, Gao, Yu-wei, Li, Min-xia, Qiu, Qiang
Format: Article
Language:English
Subjects:
Angiotensin converting enzyme inhibitors
Angiotensin Receptor Antagonists - pharmacology
Angiotensin Receptor Antagonists - therapeutic use
Angiotensin receptor blockers
Angiotensin-Converting Enzyme Inhibitors - pharmacology
Angiotensin-Converting Enzyme Inhibitors - therapeutic use
Blood Glucose - drug effects
Blood Pressure - drug effects
Endocrinology & Metabolism
Humans
Hypertension - drug therapy
Hypertension - epidemiology
Hypertension - metabolism
Insulin Resistance
Insulin sensitivity
Meta-analysis
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Summary:Highlights • We collect the data of insulin sensitivity with hypertensive patients. • A total of 203 cases of patients involved in 4 clinical studies were included. • ACEI is more effective than ARB on improve insulin sensitivity. • ACEI and ARB do not show significant differences with FPG, FPI and BP.
ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2014.11.007