Cylindroma: an update

This paper reviews the recent literature on cylindroma, a rare tumor originating from the cutaneous adnexal structures of the scalp and face. Benign cylindroma is more frequent in women, and there are solitary and multiple forms, which are autosomal. Malignant cylindroma can occur in the Brooke–Spie...

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Bibliographic Details
Published in:International journal of dermatology 2015-03, Vol.54 (3), p.275-278
Main Authors: Jordão, Clarice, de Magalhães, Taissa Canedo, Cuzzi, Tullia, Ramos-e-Silva, Marcia
Format: Article
Language:English
Subjects:
Carcinoma, Adenoid Cystic - genetics
Carcinoma, Adenoid Cystic - pathology
Facial Neoplasms - pathology
Humans
Neoplastic Syndromes, Hereditary - diagnosis
Neoplastic Syndromes, Hereditary - genetics
Scalp
Skin Neoplasms - diagnosis
Skin Neoplasms - genetics
Skin Neoplasms - pathology
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Summary:This paper reviews the recent literature on cylindroma, a rare tumor originating from the cutaneous adnexal structures of the scalp and face. Benign cylindroma is more frequent in women, and there are solitary and multiple forms, which are autosomal. Malignant cylindroma can occur in the Brooke–Spiegler syndrome, and malignant transformation is more frequent in multiple variants than in solitary tumors. Its histopathological basis is controversial, and its origin is unknown, although it is known that there is a genetic basis for onset of these tumors in Brooke–Spiegler syndrome.
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.12600