Influence of Inoculation Route on Virulence of Rhodococcus equi in Mice

Virulence of R. equi ATCC 33701 was compared by the intraperitoneal (i.p.) and intravenous (i.v.) routes in mice. Strain ATCC 33701 was more virulent by the i.v. than the i.p. route. The LD50 of strain ATCC 33701 by either route correlated with the initial number of bacteria in the liver and spleen...

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Bibliographic Details
Published in:MICROBIOLOGY and IMMUNOLOGY 1992, Vol.36(8), pp.895-898
Main Authors: Takai, Shinji, Sasaki, Yukako, Tsubaki, Shiro
Format: Article
Language:English
Subjects:
Actinomycetales Infections - mortality
Actinomycetales Infections - veterinary
Animals
Bacteriology
Biological and medical sciences
Female
Fundamental and applied biological sciences. Psychology
Injections, Intraperitoneal
Injections, Intravenous
Lethal Dose 50
Liver - microbiology
Lung - microbiology
Mice
Mice, Inbred Strains
Microbiology
Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains
Rhodococcus equi
Rhodococcus equi - pathogenicity
Time Factors
Virulence
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Summary:Virulence of R. equi ATCC 33701 was compared by the intraperitoneal (i.p.) and intravenous (i.v.) routes in mice. Strain ATCC 33701 was more virulent by the i.v. than the i.p. route. The LD50 of strain ATCC 33701 by either route correlated with the initial number of bacteria in the liver and spleen at day 0.
ISSN:0385-5600
1348-0421
DOI:10.1111/j.1348-0421.1992.tb02091.x