Synthesis, characterization, in vitro biocompatibility, and antimicrobial activity of gold, silver and gold silver alloy nanoparticles prepared from Lansium domesticum fruit peel extract

A cost-effective and eco-friendly method has been developed to form colloidal solutions of gold (AuNPs), silver (AgNPs), and gold–silver-alloy (Au–Ag-NPs) nanoparticles using Lansium domesticum (LD) fruit peel extract as a combined reducing and capping agent for the first time. The synthesized nanop...

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Bibliographic Details
Published in:Materials letters 2014-12, Vol.137, p.75-78
Main Authors: Shankar, Shiv, Jaiswal, Lily, Aparna, R.S.L., Prasad, R.G.S.V
Format: Article
Language:English
Subjects:
Antiinfectives and antibacterials
Antimicrobial activity
Biocompatibility
Biomaterials
Biotechnology
Cytotoxicity
Fruits
FTIR
Gold
Gold base alloys
Lansium domesticum
Nanoparticles
Silver
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Summary:A cost-effective and eco-friendly method has been developed to form colloidal solutions of gold (AuNPs), silver (AgNPs), and gold–silver-alloy (Au–Ag-NPs) nanoparticles using Lansium domesticum (LD) fruit peel extract as a combined reducing and capping agent for the first time. The synthesized nanoparticles were characterized by various physic-chemical techniques. AgNPs and Au–Ag-NPs demonstrated potential antimicrobial activity. All these nanoparticles showed significant biocompatibility on C2C12 cell line. In addition, cellular and LDH activities supported our biocompatibility results. The outcomes of this study indicate that, these nanoparticles could be effectively utilized in pharmaceutical, biotechnological and biomedical applications. [Display omitted] •Lansium domesticum fruit peel extract was used for the first time to fabricate AuNPs, AgNPs and Au–AgNPs without use of any hazardous chemicals.•These green synthesized nanoparticles showed excellent biocompatibility and antimicrobial activity.•These nanoparticles can be effectively used in pharmaceutical and biomedical applications for drug delivery, cancer diagnosis and imaging.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2014.08.122