Surface nanoporosity of β-type Ti–25Nb–25Zr alloy for the enhancement of protein adsorption and cell response

This paper outlines a simple method for the electrochemical anodization of β-type Ti–25Nb–25Zr (Ti25Nb25Zr) alloy with a low elastic modulus (approximately 70GPa) to alter its surface topography for bone implant applications. Surface characteristics including topography, roughness, hydrophilicity, a...

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Bibliographic Details
Published in:Surface & coatings technology 2014, Vol.259, p.206-212
Main Authors: Huang, Her-Hsiung, Wu, Chia-Ping, Sun, Ying-Sui, Yang, Wei-En, Lin, Mau-Chin, Lee, Tzu-Hsin
Format: Article
Language:English
Subjects:
Anodizing
Applied sciences
Bones
Cell response
Cross-disciplinary physics: materials science
rheology
Electrochemical anodization
Exact sciences and technology
Hydrophilicity
Materials science
Metals. Metallurgy
Nanostructure
Other surface treatments
Physics
Production techniques
Protein adsorption
Surface chemistry
Surface nanoporosity
Surface treatment
Surface treatments
Titanium base alloys
Ti–25Nb–25Zr alloy
Topography
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Summary:This paper outlines a simple method for the electrochemical anodization of β-type Ti–25Nb–25Zr (Ti25Nb25Zr) alloy with a low elastic modulus (approximately 70GPa) to alter its surface topography for bone implant applications. Surface characteristics including topography, roughness, hydrophilicity, and protein adsorption (fibronectin and albumin) were investigated. Human bone marrow mesenchymal stem cell responses, including adhesion, migration, proliferation, and mineralization, were also evaluated. The experimental results demonstrate that the electrochemical anodization process produced a nanoporous surface (pore size
ISSN:0257-8972
1879-3347
DOI:10.1016/j.surfcoat.2014.02.037