Recent advances in microchip electrophoresis for amino acid analysis

With the maturation of microfluidic technologies, microchip electrophoresis has been widely employed for amino acid analysis owing to its advantages of low sample consumption, reduced analysis time, high throughput, and potential for integration and automation. In this article, we review the recent...

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Bibliographic Details
Published in:Analytical and bioanalytical chemistry 2013-10, Vol.405 (25), p.7907-7918
Main Authors: Ou, Gaozhi, Feng, Xiaojun, Du, Wei, Liu, Xin, Liu, Bi-Feng
Format: Article
Language:English
Subjects:
Amino Acid Analysis
Amino acid sequence
Amino acids
Amino Acids - analysis
Analytical Chemistry
Animals
Automation
Biochemistry
Characterization and Evaluation of Materials
Chemistry
Chemistry and Materials Science
Electrophoresis
Electrophoresis, Microchip - instrumentation
Electrophoresis, Microchip - methods
Equipment Design
Exploration
Extraterrestrial environments
Food analysis
Food Analysis - instrumentation
Food Analysis - methods
Food Science
Foods
Glass substrates
Humans
Integrated circuits
Laboratory Medicine
Mathematical analysis
Methods
Microdialysis - instrumentation
Microdialysis - methods
Microfluidics
Monitoring/Environmental Analysis
Optical properties
Review
Sampling
Semiconductor chips
Semiconductors
Single-Cell Analysis - instrumentation
Single-Cell Analysis - methods
Technological change
Technology application
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Summary:With the maturation of microfluidic technologies, microchip electrophoresis has been widely employed for amino acid analysis owing to its advantages of low sample consumption, reduced analysis time, high throughput, and potential for integration and automation. In this article, we review the recent progress in amino acid analysis using microchip electrophoresis during the period from 2007 to 2012. Innovations in microchip materials, surface modification, sample introduction, microchip electrophoresis, and detection methods are documented, as well as nascent applications of amino acid analysis in single-cell analysis, microdialysis sampling, food analysis, and extraterrestrial exploration. Without doubt, more applications of microchip electrophoresis in amino acid analysis may be expected soon.
ISSN:1618-2642
1618-2650
DOI:10.1007/s00216-013-6830-4