Persistent Treatment Effect with Grass Synthetic Peptide Immuno-Regulatory Epitopes in Grass Allergy Symptoms in an Environmental Exposure Unit Challenge after a Second Season of Natural Pollen Exposure

Rationale Previously, we demonstrated a series of Synthetic Peptide Immuno-Regulatory Epitopes (SPIRE) derived from grass allergens resulted in a statistically significant reduction in rhinoconjunctivitis symptoms in an Environmental Exposure Unit (EEU), following a short course of treatment over 14...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB158-AB158
Main Authors: Ellis, Anne, MD, MSc, FAAAAI, Frankish, Charles W., MD, Armstrong, Kristen, MSc, Larché, Mark, PhD, Steacy, Lisa, BSc, Hafner, Rod, PhD, O'Hehir, Robyn, FRACP, PhD, FRCP, FRCPath
Format: Article
Language:English
Subjects:
Allergies
Allergy and Immunology
Pollen
Seasons
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Summary:Rationale Previously, we demonstrated a series of Synthetic Peptide Immuno-Regulatory Epitopes (SPIRE) derived from grass allergens resulted in a statistically significant reduction in rhinoconjunctivitis symptoms in an Environmental Exposure Unit (EEU), following a short course of treatment over 14 weeks and subsequent exposure to the natural grass pollen season.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1457