Recombinant Probiotic Bacillus Subtilis Spores with Surface Expression of Ara h2 Reduce Peanut-Induced Anaphylaxis in Mice

Bacillus subtilis spores are regarded as a nonpathogenic and have been widely used as a probiotic in humans. Because of their safety and stability, they have recently been used as vehicle for delivery of heterologous antigens to the gastrointestinal tract.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB29-AB29
Main Authors: Zhou, Zhenwen, PhD, Song, Ying, MD, Mao, Chaoyi, MD, Srivastava, Kamal D., PhD, Liu, Changda, PhD, Yang, Nan, PhD, Liu, Zhigang, PhD, Li, Xiu-Min, MD, MS
Format: Article
Language:English
Subjects:
Allergies
Allergy and Immunology
Food allergies
Probiotics
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Description
Summary:Bacillus subtilis spores are regarded as a nonpathogenic and have been widely used as a probiotic in humans. Because of their safety and stability, they have recently been used as vehicle for delivery of heterologous antigens to the gastrointestinal tract.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1024