Omeprazole Has Anti-Inflammatory Effects on Type 2 Cytokine-Stimulated Human Airway Epithelial Cells

Omeprazole, especially in the acid-activated form significantly (>=5[micro]M), dose-dependently suppressed IL-13-mediated eotaxin-3 mRNA expression and protein secretion from BEAS-2B cells and SNEC (p

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB81-AB81
Main Authors: Min, Jin Young, MD, PhD, Kern, Robert C., MD, Ocampo, Christopher J., MD, PhD, Homma, Tetsuya, MD, Conley, David B., MD, Shintani-Smith, Stephanie, MD, Huang, He, MS, Suh, Lydia, BSc, Norton, James E., MS, Hulse, Kathryn E., PhD, Kato, Atsushi, PhD, Schleimer, Robert P., PhD, FAAAAI, Tan, Bruce K., MD
Format: Article
Language:English
Subjects:
Allergy and Immunology
Cytokines
Medical research
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Summary:Omeprazole, especially in the acid-activated form significantly (>=5[micro]M), dose-dependently suppressed IL-13-mediated eotaxin-3 mRNA expression and protein secretion from BEAS-2B cells and SNEC (p
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1197