Isocyanates and Human Health: Multistakeholder Information Needs and Research Priorities

OBJECTIVES:To outline the knowledge gaps and research priorities identified by a broad base of stakeholders involved in the planning and participation of an international conference and research agenda workshop on isocyanates and human health held in Potomac, Maryland, in April 2013. METHODS:A multi...

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Bibliographic Details
Published in:Journal of occupational and environmental medicine 2015-01, Vol.57 (1), p.44-51
Main Authors: Lockey, James E., Redlich, Carrie A., Streicher, Robert, Pfahles-Hutchens, Andrea, Hakkinen, Pertti (Bert) J., Ellison, Gary L., Harber, Philip, Utell, Mark, Holland, John, Comai, Andrew, White, Marc
Format: Article
Language:English
Subjects:
Biomarkers
Biomedical Research
Congresses as Topic
Consensus
Consumer Product Safety
Environmental Exposure
Environmental Monitoring - methods
Epidemiology
Health Priorities
Health risk assessment
Human exposure
Humans
Isocyanates - toxicity
Models, Animal
Neoplasms - chemically induced
Occupational Diseases - chemically induced
Occupational Exposure
Occupational Health
Organic chemicals
Original Article
Respiratory Tract Diseases - chemically induced
Toxicology
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Summary:OBJECTIVES:To outline the knowledge gaps and research priorities identified by a broad base of stakeholders involved in the planning and participation of an international conference and research agenda workshop on isocyanates and human health held in Potomac, Maryland, in April 2013. METHODS:A multimodal iterative approach was used for data collection including preconference surveys, review of a 2001 consensus conference on isocyanates, oral and poster presentations, focused break-out sessions, panel discussions, and postconference research agenda workshop. RESULTS:Participants included representatives of consumer and worker health, health professionals, regulatory agencies, academic and industry scientists, labor, and trade associations. CONCLUSIONS:Recommendations were summarized regarding knowledge gaps and research priorities in the following areasworker and consumer exposures; toxicology, animal models, and biomarkers; human cancer risk; environmental exposure and monitoring; and respiratory epidemiology and disease, and occupational health surveillance.
ISSN:1076-2752
1536-5948
DOI:10.1097/JOM.0000000000000278