Biodegradable polymers for electrospinning: Towards biomedical applications

Electrospinning has received much attention recently due to the growing interest in nano-technologies and the unique material properties. This review focuses on recent progress in applying electrospinning technique in production of biodegradable nanofibers to the emerging field of biomedical. It fir...

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Bibliographic Details
Published in:Materials Science & Engineering C 2014-12, Vol.45, p.659-670
Main Authors: Kai, Dan, Liow, Sing Shy, Loh, Xian Jun
Format: Article
Language:English
Subjects:
Biocompatible Materials - chemistry
Biodegradability
Biodegradable polyesters
Biomedical materials
Biosensing Techniques
Biosensors
Drug Carriers - chemistry
Drug delivery
Drug delivery systems
Electrospinning
Electrospun nanofibers
Hydrogels - chemistry
Materials science
Nanofibers
Nanofibers - chemistry
Nanostructure
Polymers - chemistry
Tissue Engineering
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Summary:Electrospinning has received much attention recently due to the growing interest in nano-technologies and the unique material properties. This review focuses on recent progress in applying electrospinning technique in production of biodegradable nanofibers to the emerging field of biomedical. It first introduces the basic theory and parameters of nanofibers fabrication, with focus on factors affecting the morphology and fiber diameter of biodegradable nanofibers. Next, commonly electrospun biodegradable nanofibers are discussed, and the comparison of the degradation rate of nanoscale materials with macroscale materials are highlighted. The article also assesses the recent advancement of biodegradable nanofibers in different biomedical applications, including tissue engineering, drug delivery, biosensor and immunoassay. Future perspectives of biodegradable nanofibers are discussed in the last section, which emphasizes on the innovation and development in electrospinning of hydrogels nanofibers, pore size control and scale-up productions. [Display omitted] •Recent progress in applying electrospinning to biomedical field is highlighted.•The basic theory and parameters of nanofibers fabrication are discussed.•Commonly electrospun biodegradable nanofibers are introduced.•The advancement of nanofibers in various biomedical applications is assessed.
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2014.04.051