Endothelial Nitric Oxide Synthase Single Nucleotide Polymorphism and Left Ventricular Function in Early Chronic Kidney Disease: e0116160

Glu298Asp rs1799983 polymorphism in CKD patients is associated with relevant sub-clinical cardiac remodelling as detected by CMR. This gene variant may therefore represent an important genetic biomarker, and possibly highlight pathways for intervention, in these patients who are at particular risk o...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2015-01, Vol.10 (1)
Main Authors: Chand, Sourabh, Chue, Colin D, Edwards, Nicola C, Hodson, James, Simmonds, Matthew J, Hamilton, Alexander, Gough, Stephen CL, Harper, Lorraine, Steeds, Rick P, Townend, Jonathan N
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Glu298Asp rs1799983 polymorphism in CKD patients is associated with relevant sub-clinical cardiac remodelling as detected by CMR. This gene variant may therefore represent an important genetic biomarker, and possibly highlight pathways for intervention, in these patients who are at particular risk of worsening cardiac disease as their renal dysfunction progresses.
ISSN:1932-6203
DOI:10.1371/journal.pone.0116160