Long-term cannabis abuse and early-onset cannabis use increase the severity of cocaine withdrawal during detoxification and rehospitalization rates due to cocaine dependence

Highlights • Long-term cannabis abuse is implicated in worse cocaine withdrawal during detoxification. • Early-onset is related to worse cocaine withdrawal during detoxification. • Long-term cannabis abuse predicted higher number of re-hospitalization due to cocaine dependence. • Cannabis use should...

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Bibliographic Details
Published in:Drug and alcohol dependence 2014-11, Vol.144, p.153-159
Main Authors: Viola, Thiago Wendt, Tractenberg, Saulo Gantes, Wearick-Silva, Luis Eduardo, Rosa, Caroline Silva de Oliveira, Pezzi, Júlio Carlos, Grassi-Oliveira, Rodrigo
Format: Article
Language:English
Subjects:
Addictive behavior
Adolescent
Adult
Cannabis
Cocaine
Cocaine - adverse effects
Cocaine-Related Disorders - diagnosis
Cocaine-Related Disorders - epidemiology
Cocaine-Related Disorders - therapy
Female
Follow-Up Studies
Hospitalization
Humans
Marijuana Abuse - diagnosis
Marijuana Abuse - epidemiology
Marijuana Abuse - therapy
Mental Health Services - trends
Patient Readmission - trends
Psychiatry
Severity of Illness Index
Substance withdrawal syndrome
Substance Withdrawal Syndrome - diagnosis
Substance Withdrawal Syndrome - epidemiology
Substance Withdrawal Syndrome - therapy
Time Factors
Young Adult
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Summary:Highlights • Long-term cannabis abuse is implicated in worse cocaine withdrawal during detoxification. • Early-onset is related to worse cocaine withdrawal during detoxification. • Long-term cannabis abuse predicted higher number of re-hospitalization due to cocaine dependence. • Cannabis use should be considered an adverse factor to cocaine withdrawal.
ISSN:0376-8716
1879-0046
DOI:10.1016/j.drugalcdep.2014.09.003