Evaluation of the Elecsys® Anti-HCV II assay for routine hepatitis C virus screening of different Asian Pacific populations and detection of early infection

Highlights • Evaluation of the Elecsys® Anti-HCV II assay as a routine screening assay in Asia. • Elecsys® Anti-HCV II shortens the window between infection and antibody detection. • The Elecsys® Anti-HCV II assay had a sensitivity of 100% (322/322). • The specificity of the Elecsys® Anti-HCV II ass...

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Bibliographic Details
Published in:Journal of clinical virology 2015-03, Vol.64, p.20-27
Main Authors: Yoo, Soo Jin, Wang, Lan Lan, Ning, Hsiao-Chen, Tao, Chuan Min, Hirankarn, Nattiya, Kuakarn, Sunida, Yang, Ruifeng, Han, Tae Hee, Chan, Raymond C, Hussain, Baizurah Mohd, Hussin, Hazilawati, Muliaty, Dewi, Shen, Lisong, Liu, Hongjing, Wei, Lai
Format: Article
Language:English
Subjects:
Allergy and Immunology
Antibodies, Viral - blood
Asia
Assay
Early Diagnosis
Elecsys® Anti-HCV II
Hepacivirus - immunology
Hepatitis C - diagnosis
Humans
Immunoassay - methods
Infectious Disease
Luminescent Measurements
Mass Screening
Reagent Kits, Diagnostic
Sensitivity
Sensitivity and Specificity
Seroconversion sensitivity
Specificity
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Summary:Highlights • Evaluation of the Elecsys® Anti-HCV II assay as a routine screening assay in Asia. • Elecsys® Anti-HCV II shortens the window between infection and antibody detection. • The Elecsys® Anti-HCV II assay had a sensitivity of 100% (322/322). • The specificity of the Elecsys® Anti-HCV II assay was 99.66%. • Elecsys® Anti-HCV II is suitable for use as a routine screening assay in Asia.
ISSN:1386-6532
1873-5967
DOI:10.1016/j.jcv.2014.12.015