Shear-wave elastography and immunohistochemical profiles in invasive breast cancer: Evaluation of maximum and mean elasticity values

Highlights • Shear wave elastography provides a quantitative assessment of the hardness of breast lesions. • The hardness of breast lesions correlates with lesion size: larger lesions are harder than smaller ones. • Histologic type and grade do not correlate clearly with elastography parameters. • H...

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Bibliographic Details
Published in:European journal of radiology 2015-04, Vol.84 (4), p.617-622
Main Authors: Ganau, Sergi, Andreu, Francisco Javier, Escribano, Fernanda, Martín, Amaya, Tortajada, Lidia, Villajos, Maite, Baré, Marisa, Teixidó, Milagros, Ribé, Judit, Sentís, Melcior
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Breast cancer molecular subtypes
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Breast Neoplasms - ultrastructure
Elasticity Imaging Techniques - methods
Elastography
Female
Humans
Middle Aged
Prospective Studies
Radiology
Reproducibility of Results
Shear-wave
Ultrasound
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Summary:Highlights • Shear wave elastography provides a quantitative assessment of the hardness of breast lesions. • The hardness of breast lesions correlates with lesion size: larger lesions are harder than smaller ones. • Histologic type and grade do not correlate clearly with elastography parameters. • HER2, luminal B HER2+, and triple-negative tumors have lower maximum hardness and mean hardness than other tumor types. • Half the tumors classified as BI-RADS 3 were luminal A and half were HER2.
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2014.12.020