Preparation and characterization of collagen–hydroxyapatite/pectin composite

Pectin, a kind of plant polysaccharide, was introduced into collagen–hydroxyapatite composite system, and prepared collagen–hydroxyapatite/pectin (Col–HA/pectin) composite in situ. The structure of the composite was investigated by XRD, SEM, and FT-IR. The mechanical properties, water absorption, en...

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Bibliographic Details
Published in:International journal of biological macromolecules 2015-03, Vol.74, p.218-223
Main Authors: Wenpo, Feng, Gaofeng, Liang, Shuying, Feng, Yuanming, Qi, Keyong, Tang
Format: Article
Language:English
Subjects:
Animals
Biocompatible Materials - chemistry
Bone repairing material
Bone Substitutes - chemistry
Collagen - chemistry
Collagen–hydroxyapatite/pectin composite
Durapatite - chemistry
Hydrophobic and Hydrophilic Interactions
In situ synthesis
Materials Testing
Pectins - chemistry
Rabbits
Spectroscopy, Fourier Transform Infrared
X-Ray Diffraction
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Summary:Pectin, a kind of plant polysaccharide, was introduced into collagen–hydroxyapatite composite system, and prepared collagen–hydroxyapatite/pectin (Col–HA/pectin) composite in situ. The structure of the composite was investigated by XRD, SEM, and FT-IR. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity of the composite were investigated as well. The results show that the inorganic substance in the composite materials is hydroxyapatite in relatively low crystallinity. A new interface appeared by the interaction among hydroxyapatite and collagen–pectin, and formed smooth fine particles. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity indicate a potential use in bone replacement for the new composite.
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2014.11.031