Multi-modality imaging for stent edge assessment

Optical coherence tomography (OCT) has a sufficiently high resolution to allow assessment of stent edge dissection (ED). The aims of the present study were as follows: (1) evaluation of the frequency of stent ED using OCT; (2) comparison of stent ED detection rates obtained using angiography, intrav...

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Bibliographic Details
Published in:Heart and vessels 2015-03, Vol.30 (2), p.162-168
Main Authors: Ann, Soe Hee, Lim, Kyung Hun, De Jin, Cai, Shin, Eun-Seok
Format: Article
Language:English
Subjects:
Aged
Biomedical Engineering and Bioengineering
Cardiac Surgery
Cardiology
Coronary Angiography
Coronary Artery Disease - diagnosis
Coronary Artery Disease - therapy
Coronary Vessels - diagnostic imaging
Coronary Vessels - pathology
Female
Humans
Male
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Multimodal Imaging - methods
Necrosis
Original Article
Percutaneous Coronary Intervention - adverse effects
Percutaneous Coronary Intervention - instrumentation
Predictive Value of Tests
Retrospective Studies
Stents
Tomography, Optical Coherence
Treatment Outcome
Ultrasonography, Interventional
Vascular Calcification - diagnosis
Vascular Calcification - therapy
Vascular Surgery
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Summary:Optical coherence tomography (OCT) has a sufficiently high resolution to allow assessment of stent edge dissection (ED). The aims of the present study were as follows: (1) evaluation of the frequency of stent ED using OCT; (2) comparison of stent ED detection rates obtained using angiography, intravascular ultrasound (IVUS), and OCT; and (3) IVUS-Virtual Histology (IVUS-VH) evaluation of plaque composition at the site of stent EDs detected by OCT after percutaneous coronary intervention (PCI). Fifty-eight consecutive patients (59 lesions, 100 stent edges) who underwent balloon-expandable stent implantation and post-stent assessment with OCT and IVUS-VH were included. OCT revealed stent ED in 24.0 % (24 of 100) of stent edges after PCI with a balloon-expandable stent. In contrast, ED was detected in only 3.0 % (3 of 100) of stent edges using angiography and 4.0 % (4 of 100) of stent edges using IVUS. Plaque evaluation using IVUS-VH showed that the percent necrotic core (21.2 ± 8.3 vs. 13.4 ± 10.7 %, p  = 0.001) and absolute dense calcium (2.9 ± 2.4 vs. 1.3 ± 2.2 mm 3 , p  = 0.0104) and dense calcium (13.8 ± 9.3 vs. 5.4 ± 5.8 %, p  
ISSN:0910-8327
1615-2573
DOI:10.1007/s00380-014-0467-x