In Vitro Dose-Response Study of the Effect of Cadmium on Eel (Anguilla anguilla) Gill Na super(+)/K super(+)-ATPase Activities

Eels, which migrate through waters having wide variations in salinity and a high likelihood of heavy metal contamination were used in an in vitro study of the effect of cadmium on the activity of sodium/potassium ATPase in the gills. Eels were acclimated to either fresh or salt water, exposed to var...

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Bibliographic Details
Published in:Ecotoxicology and environmental safety 1994-06, Vol.28 (1), p.43-43
Main Authors: Lemaire-Gony, Sylviane, Mayer-Gostan, Nicole
Format: Article
Language:English
Subjects:
Anguilla anguilla
Freshwater
Marine
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Summary:Eels, which migrate through waters having wide variations in salinity and a high likelihood of heavy metal contamination were used in an in vitro study of the effect of cadmium on the activity of sodium/potassium ATPase in the gills. Eels were acclimated to either fresh or salt water, exposed to various concentrations of Cd, and studied for effects on enzyme activity. At the highest freshwater and saltwater concentrations of Cd, decreases of 40 and 25%, respectively, were demonstrated in basal activity, as measured by magnesium ATPase activity. A dose-dependent inhibition of Na/K ATPase activity was demonstrated by exposure to Cd. At a concentration of 146 nM, 50% of the activity was inhibited, as measured by two different techniques, for eels adapted to both saltwater and freshwater.
ISSN:0147-6513