Molecular evidence and high genetic diversity of shrew-borne Seewis virus in Slovenia

Seewis virus, the shrew-borne hantavirus from Sorex araneus, has been molecularly detected in reservoir hosts in many different central European countries and Russia. Slovenia is a known endemic country for rodent-borne hantaviruses, therefore the aim of the study was to investigate the presence of...

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Bibliographic Details
Published in:Virus research 2013-10, Vol.177 (1), p.113-117
Main Authors: Resman, Katarina, Korva, Miša, Fajs, Luka, Zidarič, Tanja, Trilar, Tomi, Županc, Tatjana Avšič
Format: Article
Language:English
Subjects:
Animals
Araneus
disease reservoirs
Disease Reservoirs - virology
Genetic Variation
Hantavirus
Hantavirus - classification
Hantavirus - genetics
Hantavirus - isolation & purification
insectivores
Molecular Sequence Data
Phylogeny
Seewis virus
shrews
Shrews - virology
Slovenia
Sorex araneus
Viral Proteins - genetics
viruses
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Summary:Seewis virus, the shrew-borne hantavirus from Sorex araneus, has been molecularly detected in reservoir hosts in many different central European countries and Russia. Slovenia is a known endemic country for rodent-borne hantaviruses, therefore the aim of the study was to investigate the presence of shrew-borne hantaviruses in insectivores. Viral L, S and M segment have been recovered only from tissue samples of 7 S. araneus, despite several shrew species were tested. Phylogenetic analysis showed high genetic diversity of SWSV in Slovenia, ranging from 3 to 19.4% for different viral segments. The most divergent were M segment sequences, with 19.4% nucleotide divergence among Slovenian strains. Above that, different SWSV strains from Slovenia do not group into separate geographic clusters. While three separate genetic clades were determined, two of them were simultaneously present in one location at the same time.
ISSN:0168-1702
1872-7492
DOI:10.1016/j.virusres.2013.07.011