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The major predictors of amputation and length of stay in diabetic patients with acute foot ulceration
Summary Background Diabetic foot infections are associated with substantial morbidity and mortality. Prediction of diabetic foot ulcer outcome may be helpful for optimizing management strategy. This study aimed to determine the major predictors of amputation and length of stay in diabetic patients w...
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Published in: | Wiener Klinische Wochenschrift 2015-01, Vol.127 (1-2), p.45-50 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Background
Diabetic foot infections are associated with substantial morbidity and mortality. Prediction of diabetic foot ulcer outcome may be helpful for optimizing management strategy. This study aimed to determine the major predictors of amputation and length of stay in diabetic patients with acute foot ulceration.
Methods
A total of 55 type 2 diabetic patients with diabetic foot infection were enrolled. The patients were evaluated according to the Infectious Diseases Society of America and International Working Group on the Diabetic Foot criteria and also the Wagner’s classification. Blood samples were taken at the start of hospitalization for the measurement of glucose, hemoglobin A1C (HbA
1
C), white blood cells (WBC), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR). Length of stay in hospital was recorded.
Results
WBC and CRP were significantly higher in lower-extremity amputation (LEA) group (
p
= 0.001 and
p
= 0.008, respectively); also, ESR was higher in this group, but there was no statistical significance. Wagner grade and infection severity were significantly higher in the LEA group as compared with the non-LEA group (both
p
values |
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ISSN: | 0043-5325 1613-7671 |
DOI: | 10.1007/s00508-014-0630-5 |