Muscle ultrasonography as an additional diagnostic tool for the diagnosis of amyotrophic lateral sclerosis

Highlights • Muscle ultrasonography (MUS) is highly sensitive in detecting fasciculations—even in the muscles of full strength—and fibrillations, especially in the bulbar muscles of patients with amyotrophic lateral sclerosis (ALS). • MUS shows significantly increased echo intensity and fasciculatio...

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Bibliographic Details
Published in:Clinical neurophysiology 2015-04, Vol.126 (4), p.820-827
Main Authors: Grimm, A, Prell, T, Décard, B.F, Schumacher, U, Witte, O.W, Axer, H, Grosskreutz, J
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis - diagnostic imaging
Amyotrophic Lateral Sclerosis - physiopathology
Electromyography
Electromyography - methods
Female
Humans
Male
Middle Aged
Muscle, Skeletal - diagnostic imaging
Muscle, Skeletal - physiopathology
Myosonography
Neurology
Neuromuscular
Ultrasonography
Ultrasound
Young Adult
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Summary:Highlights • Muscle ultrasonography (MUS) is highly sensitive in detecting fasciculations—even in the muscles of full strength—and fibrillations, especially in the bulbar muscles of patients with amyotrophic lateral sclerosis (ALS). • MUS shows significantly increased echo intensity and fasciculations in clinically and electrophysiologically affected and unaffected muscles in ALS patients. • When combined with electromyography (EMG), MUS can provide additional information about specific muscles and increase the diagnostic yield.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2014.06.052