Small Renal Masses Managed With Active Surveillance: Predictors of Tumor Growth Rate After Long-Term Follow-Up

Micro-Abstract Active surveillance (AS) could be a valid alternative for the management of small renal masses (SRMs) in elderly or comorbid patients. The natural history of SRMs has not been completely clarified and, to date, no convincing predictors of tumor growth rate or biological behavior of sm...

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Bibliographic Details
Published in:Clinical genitourinary cancer 2015-04, Vol.13 (2), p.e87-e92
Main Authors: Schiavina, Riccardo, Borghesi, Marco, Dababneh, Hussam, Bianchi, Lorenzo, Longhi, Barbara, Diazzi, Davide, Monti, Carlo, La Manna, Gaetano, Martorana, Giuseppe, Brunocilla, Eugenio
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Comorbidity
Delayed surgery
Disease Progression
Female
Hematology, Oncology and Palliative Medicine
Humans
Kidney - pathology
Logistic Models
Male
Neoplasm Staging
Predictors
Renal cell carcinoma
Retrospective Studies
Risk Factors
Sex Factors
Small cortical tumors
Surveillance protocol
Tumor Burden
Urology
Watchful Waiting
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Summary:Micro-Abstract Active surveillance (AS) could be a valid alternative for the management of small renal masses (SRMs) in elderly or comorbid patients. The natural history of SRMs has not been completely clarified and, to date, no convincing predictors of tumor growth rate or biological behavior of small cortical neoplasms have been described. In our cohort, male sex (hazard ratio [HR], 1.70; P  = .04) and symptomatic presentation (HR, 1.85; P  = .02) were found to be significant predictors of tumor growth rates during AS.
ISSN:1558-7673
1938-0682
DOI:10.1016/j.clgc.2014.08.006