The Epidemiology of Blood Pressure and Its Worldwide Management

Despite the vast amount of evidence on the benefits of blood pressure lowering accumulated to date, elevated blood pressure is still the leading risk factor for disease and disability worldwide. The purpose of this review is to summarize the epidemiological evidence underpinning the association betw...

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Bibliographic Details
Published in:Circulation research 2015-03, Vol.116 (6), p.925-936
Main Authors: Rahimi, Kazem, Emdin, Connor A, MacMahon, Stephen
Format: Article
Language:English
Subjects:
Aging - physiology
Antihypertensive Agents - therapeutic use
Blood Pressure
Cardiovascular Diseases - epidemiology
Cohort Studies
Comorbidity
Developed Countries
Developing Countries
Diastole
Disease Management
Global Health
Healthcare Disparities
Humans
Hypertension - drug therapy
Hypertension - economics
Hypertension - epidemiology
Income
Kidney Diseases - epidemiology
Meta-Analysis as Topic
Risk Factors
Systole
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Description
Summary:Despite the vast amount of evidence on the benefits of blood pressure lowering accumulated to date, elevated blood pressure is still the leading risk factor for disease and disability worldwide. The purpose of this review is to summarize the epidemiological evidence underpinning the association between blood pressure and a range of conditions. This review focuses on the association between systolic and diastolic blood pressures and the risk of cardiovascular and renal disease. Evidence for and against the existence of a J-shaped curve association between blood pressure and cardiovascular risk, and differences in the predictive power of systolic, diastolic, and pulse pressure, are described. In addition, global and regional trends in blood pressure levels and management of hypertension are reviewed.
ISSN:0009-7330
1524-4571
DOI:10.1161/CIRCRESAHA.116.304723