Laparoscopic Versus Open Distal Pancreatectomy for Ductal Adenocarcinoma: A Systematic Review and Meta-Analysis

Background Laparoscopic distal pancreatectomy was proposed as an oncologically safe approach for pancreatic ductal adenocarcinoma. Methods A systematic review of the studies comparing laparoscopic and open distal pancreatectomy was conducted. The primary endpoint was an R0 resection rate. The second...

Full description

Saved in:
Bibliographic Details
Published in:Journal of gastrointestinal surgery 2015-04, Vol.19 (4), p.770-781
Main Authors: Ricci, Claudio, Casadei, Riccardo, Taffurelli, Giovanni, Toscano, Fabrizio, Pacilio, Carlo Alberto, Bogoni, Selene, D’Ambra, Marielda, Pagano, Nico, Di Marco, Maria Cristina, Minni, Francesco
Format: Article
Language:English
Subjects:
Carcinoma, Pancreatic Ductal - surgery
Fistula
Gastroenterology
Hospitals
Humans
Laparoscopy
Lymphatic system
Medical Subject Headings-MeSH
Medicine
Medicine & Public Health
Meta-analysis
Mortality
Pancreatectomy - methods
Pancreatic cancer
Pancreatic Neoplasms - surgery
Review Article
Surgery
Systematic review
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Laparoscopic distal pancreatectomy was proposed as an oncologically safe approach for pancreatic ductal adenocarcinoma. Methods A systematic review of the studies comparing laparoscopic and open distal pancreatectomy was conducted. The primary endpoint was an R0 resection rate. The secondary endpoints were intra- and postoperative results, tumour size, mean harvested lymph node, number of patients eligible for adjuvant therapy and overall survival. Results Five comparative case control studies involving 261 patients (30.7 % laparoscopic and 69.3 % open) who underwent a distal pancreatectomy were included. The R0 resection rate was similar between the two groups ( P  = 0.53). The laparoscopic group had longer operative times ( P  = 0.04), lesser blood loss ( P  = 0.01), a shorter hospital stay ( P  
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-014-2721-z