Impact of Rosuvastatin on Contrast-Induced Acute Kidney Injury in Patients at High Risk for Nephropathy Undergoing Elective Angiography

Although statins have been shown to prevent contrast-induced acute kidney injury in patients with acute coronary syndromes, the benefit of statins is not known for patients at high risk for nephropathy who undergo elective coronary angiography. Two hundred twenty consecutive statin-naive patients wi...

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Bibliographic Details
Published in:The American journal of cardiology 2015-04, Vol.115 (7), p.867-871
Main Authors: Abaci, Okay, MD, Arat Ozkan, Alev, MD, Kocas, Cuneyt, MD, Cetinkal, Gokhan, MD, Sukru Karaca, Osman, MD, Baydar, Onur, MD, Kaya, Aysem, PhD, Gurmen, Tevfik, MD
Format: Article
Language:English
Subjects:
Acute Coronary Syndrome - diagnostic imaging
Acute Coronary Syndrome - drug therapy
Acute coronary syndromes
Acute Kidney Injury - chemically induced
Acute Kidney Injury - physiopathology
Acute Kidney Injury - prevention & control
Age
Aged
Cardiology
Cardiovascular
Cardiovascular disease
Confidence intervals
Consent
Contrast agents
Contrast Media - adverse effects
Coronary Angiography - adverse effects
Coronary Angiography - methods
Coronary vessels
Diabetes
Diuretics
Drug therapy
Female
Fluorobenzenes - therapeutic use
Follow-Up Studies
Glomerular Filtration Rate - drug effects
Heart attacks
Heart failure
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Male
Medical imaging
Mortality
Prognosis
Pyrimidines - therapeutic use
Retrospective Studies
Risk Factors
Rosuvastatin Calcium
Statins
Sulfonamides - therapeutic use
Variables
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Description
Summary:Although statins have been shown to prevent contrast-induced acute kidney injury in patients with acute coronary syndromes, the benefit of statins is not known for patients at high risk for nephropathy who undergo elective coronary angiography. Two hundred twenty consecutive statin-naive patients with chronic kidney disease (estimated glomerular filtration rate
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2015.01.007