Changes in patterns of alkaline serine protease and bacilysin formation caused by common effectors of sporulation in Bacillus subtilis 168

Bacilysin biosynthesis and alkaline serine protease production in Bacillus subtilis 168 were monitored and compared in batch cultures when various effectors of sporulation were added at different stages of growth in a medium containing sucrose and glutamate. Depending on the time of addition, glucos...

Full description

Saved in:
Bibliographic Details
Published in:Current microbiology 1992, Vol.24 (3), p.129-135
Main Authors: BASALP, A, ÖZCENGIZ, G, GÜRDAL ALAEDDINOGLU, N
Format: Article
Language:English
Subjects:
Bacillus subtilis
Bacteriology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Growth, nutrition, cell differenciation
Microbiology
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Bacilysin biosynthesis and alkaline serine protease production in Bacillus subtilis 168 were monitored and compared in batch cultures when various effectors of sporulation were added at different stages of growth in a medium containing sucrose and glutamate. Depending on the time of addition, glucose affected sporulation and serine protease formation to the same extent, but had no effect on bacilysin production. Ammonium and L-alanine additions suppressed all three processes. Casamino acids severely interfered with bacilysin formation and sporulation, but not with protease formation. Decoyinine, a well-known inducer of sporulation, induced protease formation as well, but did not affect bacilysin biosynthesis. The extent of the observed effects depended largely on the time of metabolite additions. The results are discussed with reference to a possible coregulation of sporulation and the formation of bacilysin and alkaline serine protease in B. subtilis .
ISSN:0343-8651
1432-0991
DOI:10.1007/BF01568977