Chemistry of odortypes in mice : fractionation and bioassay

Mice can discriminate samples of urine obtained from two groups of inbred mice that are genetically identical except in their major histocompatibility complex (MHC) haplotype (congenic mice), whereas they cannot distinguish urine samples from two genetically identical groups of mice. Chemical fracti...

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Bibliographic Details
Published in:Journal of chemical ecology 1993-03, Vol.19 (3), p.569-579
Main Authors: SINGER, A. G, TSUCHIYA, H, WELLINGTON, J. L, BEAUCHAMP, G. K, YAMAZAKI, K
Format: Article
Language:English
Subjects:
Animal and plant ecology
Animal, plant and microbial ecology
Animals
Autoecology
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Mammalia
Vertebrata
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Summary:Mice can discriminate samples of urine obtained from two groups of inbred mice that are genetically identical except in their major histocompatibility complex (MHC) haplotype (congenic mice), whereas they cannot distinguish urine samples from two genetically identical groups of mice. Chemical fractions of urine samples obtained from MHC congenic mice were tested in a Y-maze olfactometer using a method modified to accommodate the bioassay to chemical fractions that might differ in sensory properties from the unfractionated urine. Fractions depleted in protein by several methods were consistently discriminable by mice in the Y maze, providing a direct demonstration that the airborne MHC genotype information can be conveyed by volatile compounds alone.
ISSN:0098-0331
1573-1561
DOI:10.1007/BF00994326