Microbial production of propionic acid and vitamin B sub(12) using molasses or sugar

With a cell concentration of 125 g dry biomass 1 super(-1) and a dilution rate of 0.1 h super(-1), Propionibacterium acidipropionici produces 30 g propionic acid l super(-1) from sugar with a productivity of 3 g l super(-1) h super(-1). The yield of propionic acid is approx. 0.36-0.45 g propionic ac...

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Bibliographic Details
Published in:Applied microbiology and biotechnology 1994-01, Vol.41 (4), p.378-383
Main Authors: Quesada-Chanto, A, Afschar, A S, Wagner, F
Format: Article
Language:English
Subjects:
Propionibacterium acidipropionici
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Summary:With a cell concentration of 125 g dry biomass 1 super(-1) and a dilution rate of 0.1 h super(-1), Propionibacterium acidipropionici produces 30 g propionic acid l super(-1) from sugar with a productivity of 3 g l super(-1) h super(-1). The yield of propionic acid is approx. 0.36-0.45 g propionic acid g super(-1) sucrose and is independent of the dilution rate and cell concentration. Acetic acid is an unwanted by-product in the production of propionic acid. The concentration of acetic acid only increases slightly when the cell concentration is increased. A two-stage fermentation process was developed for the conversion of sugar or molasses of various types to propionic acid and vitamin B sub(12). By fermentation of blackstrap molasses (from sugar beet and sugar cane) in the first fermentation stage 17.7 g propionic acid l super(-1) with a yield of 0.5 g propionic acid g super(-1) carbohydrate was produced with a dilution rate of 0.25 h super(-1). In the second stage 49 mg vitamin B sub(12) l super(-1) was produced at a dilution rate of 0.03 h super(-1).
ISSN:0175-7598