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Ethnic Differences Among Implantable Cardioverter Defibrillators Recipients in Israel
Heart failure is an increasingly common condition arising from a variety of different pathophysiological processes. Little is known about the unique features of Israeli Arabs who present with heart failure and who undergo cardiac device implantation. The study population comprised of 4,671 patients...
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Published in: | The American journal of cardiology 2015-04, Vol.115 (8), p.1102-1106 |
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creator | Sabbag, Avi, MD Suleiman, Mahmoud, MD Glick, Aharon, MD Medina, Aharon, MD Golovchiner, Gregory, MD Steiner, Hillel, MD Arad, Michael, MD Goldenberg, Ilan, MD Glikson, Michael, MD Beinart, Roy, MD |
description | Heart failure is an increasingly common condition arising from a variety of different pathophysiological processes. Little is known about the unique features of Israeli Arabs who present with heart failure and who undergo cardiac device implantation. The study population comprised of 4,671 patients who were enrolled in the national Israeli Implantable Cardioverter Defibrillator registry. We compared demographic, clinical, and echocardiographic characteristics; device-related indications; and outcomes between Israeli Arabs (n = 733) and Jews (n = 3,938), who were enrolled in the registry from July 2010 through December 2013. Israeli Arabs constituted 15.7% of the study population. They were younger at presentation compared with Jews (57 ± 15 vs 66 ± 12 years, respectively; p |
doi_str_mv | 10.1016/j.amjcard.2015.01.538 |
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Little is known about the unique features of Israeli Arabs who present with heart failure and who undergo cardiac device implantation. The study population comprised of 4,671 patients who were enrolled in the national Israeli Implantable Cardioverter Defibrillator registry. We compared demographic, clinical, and echocardiographic characteristics; device-related indications; and outcomes between Israeli Arabs (n = 733) and Jews (n = 3,938), who were enrolled in the registry from July 2010 through December 2013. Israeli Arabs constituted 15.7% of the study population. They were younger at presentation compared with Jews (57 ± 15 vs 66 ± 12 years, respectively; p <0.001), with a greater burden of co-morbidities, including diabetes mellitus and chronic obstructive lung disease and smoking. In addition, Arab patients had a greater frequency of non-ischemic cardiomyopathy (40.2% vs 24.6%, respectively; p <0.001), which was associated with a greater frequency of familial history of sudden cardiac death. During 15 ± 9 month follow-up, the mortality rates and appropriate device therapy were similar in both ethnic groups. In conclusion, Israeli Arab patients implanted with implantable cardioverter defibrillators display unique clinical features with greater prevalence of non-ischemic cardiomyopathy characterized by an early-onset and rapid deterioration.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2015.01.538</identifier><identifier>PMID: 25743210</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Age ; Aged ; Arab people ; Cardiac arrhythmia ; Cardiomyopathy ; Cardiovascular ; Cardiovascular disease ; Cause of Death - trends ; Death, Sudden, Cardiac - ethnology ; Death, Sudden, Cardiac - prevention & control ; Defibrillators, Implantable ; Diabetes ; Disease prevention ; Diuretics ; Ethnic Groups ; Ethnicity ; Family medical history ; Female ; Follow-Up Studies ; Heart attacks ; Heart failure ; Heart Failure - ethnology ; Heart Failure - therapy ; Humans ; Israel - epidemiology ; Jewish people ; Male ; Middle Aged ; Mortality ; Multivariate analysis ; Population ; Prevalence ; Prognosis ; Prospective Studies ; Survival Rate - trends ; Variables</subject><ispartof>The American journal of cardiology, 2015-04, Vol.115 (8), p.1102-1106</ispartof><rights>Elsevier Inc.</rights><rights>2015 Elsevier Inc.</rights><rights>Copyright © 2015 Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Apr 15, 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c518t-5af79587d40bf4b734cb613016af7dfc17c60b6229ff6a78d577c8c1a55c3ae93</citedby><cites>FETCH-LOGICAL-c518t-5af79587d40bf4b734cb613016af7dfc17c60b6229ff6a78d577c8c1a55c3ae93</cites><orcidid>0000-0003-4295-6679</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25743210$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sabbag, Avi, MD</creatorcontrib><creatorcontrib>Suleiman, Mahmoud, MD</creatorcontrib><creatorcontrib>Glick, Aharon, MD</creatorcontrib><creatorcontrib>Medina, Aharon, MD</creatorcontrib><creatorcontrib>Golovchiner, Gregory, MD</creatorcontrib><creatorcontrib>Steiner, Hillel, MD</creatorcontrib><creatorcontrib>Arad, Michael, MD</creatorcontrib><creatorcontrib>Goldenberg, Ilan, MD</creatorcontrib><creatorcontrib>Glikson, Michael, MD</creatorcontrib><creatorcontrib>Beinart, Roy, MD</creatorcontrib><title>Ethnic Differences Among Implantable Cardioverter Defibrillators Recipients in Israel</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Heart failure is an increasingly common condition arising from a variety of different pathophysiological processes. Little is known about the unique features of Israeli Arabs who present with heart failure and who undergo cardiac device implantation. The study population comprised of 4,671 patients who were enrolled in the national Israeli Implantable Cardioverter Defibrillator registry. We compared demographic, clinical, and echocardiographic characteristics; device-related indications; and outcomes between Israeli Arabs (n = 733) and Jews (n = 3,938), who were enrolled in the registry from July 2010 through December 2013. Israeli Arabs constituted 15.7% of the study population. They were younger at presentation compared with Jews (57 ± 15 vs 66 ± 12 years, respectively; p <0.001), with a greater burden of co-morbidities, including diabetes mellitus and chronic obstructive lung disease and smoking. In addition, Arab patients had a greater frequency of non-ischemic cardiomyopathy (40.2% vs 24.6%, respectively; p <0.001), which was associated with a greater frequency of familial history of sudden cardiac death. During 15 ± 9 month follow-up, the mortality rates and appropriate device therapy were similar in both ethnic groups. In conclusion, Israeli Arab patients implanted with implantable cardioverter defibrillators display unique clinical features with greater prevalence of non-ischemic cardiomyopathy characterized by an early-onset and rapid deterioration.</description><subject>Age</subject><subject>Aged</subject><subject>Arab people</subject><subject>Cardiac arrhythmia</subject><subject>Cardiomyopathy</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Cause of Death - trends</subject><subject>Death, Sudden, Cardiac - ethnology</subject><subject>Death, Sudden, Cardiac - prevention & control</subject><subject>Defibrillators, Implantable</subject><subject>Diabetes</subject><subject>Disease prevention</subject><subject>Diuretics</subject><subject>Ethnic Groups</subject><subject>Ethnicity</subject><subject>Family medical history</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart attacks</subject><subject>Heart failure</subject><subject>Heart Failure - 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trends</topic><topic>Death, Sudden, Cardiac - ethnology</topic><topic>Death, Sudden, Cardiac - prevention & control</topic><topic>Defibrillators, Implantable</topic><topic>Diabetes</topic><topic>Disease prevention</topic><topic>Diuretics</topic><topic>Ethnic Groups</topic><topic>Ethnicity</topic><topic>Family medical history</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart attacks</topic><topic>Heart failure</topic><topic>Heart Failure - ethnology</topic><topic>Heart Failure - therapy</topic><topic>Humans</topic><topic>Israel - epidemiology</topic><topic>Jewish people</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Multivariate analysis</topic><topic>Population</topic><topic>Prevalence</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Survival Rate - trends</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sabbag, Avi, MD</creatorcontrib><creatorcontrib>Suleiman, Mahmoud, MD</creatorcontrib><creatorcontrib>Glick, Aharon, MD</creatorcontrib><creatorcontrib>Medina, Aharon, MD</creatorcontrib><creatorcontrib>Golovchiner, Gregory, MD</creatorcontrib><creatorcontrib>Steiner, Hillel, MD</creatorcontrib><creatorcontrib>Arad, Michael, MD</creatorcontrib><creatorcontrib>Goldenberg, Ilan, MD</creatorcontrib><creatorcontrib>Glikson, Michael, MD</creatorcontrib><creatorcontrib>Beinart, Roy, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest research library</collection><collection>Biochemistry Abstracts 1</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - 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Little is known about the unique features of Israeli Arabs who present with heart failure and who undergo cardiac device implantation. The study population comprised of 4,671 patients who were enrolled in the national Israeli Implantable Cardioverter Defibrillator registry. We compared demographic, clinical, and echocardiographic characteristics; device-related indications; and outcomes between Israeli Arabs (n = 733) and Jews (n = 3,938), who were enrolled in the registry from July 2010 through December 2013. Israeli Arabs constituted 15.7% of the study population. They were younger at presentation compared with Jews (57 ± 15 vs 66 ± 12 years, respectively; p <0.001), with a greater burden of co-morbidities, including diabetes mellitus and chronic obstructive lung disease and smoking. In addition, Arab patients had a greater frequency of non-ischemic cardiomyopathy (40.2% vs 24.6%, respectively; p <0.001), which was associated with a greater frequency of familial history of sudden cardiac death. During 15 ± 9 month follow-up, the mortality rates and appropriate device therapy were similar in both ethnic groups. In conclusion, Israeli Arab patients implanted with implantable cardioverter defibrillators display unique clinical features with greater prevalence of non-ischemic cardiomyopathy characterized by an early-onset and rapid deterioration.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>25743210</pmid><doi>10.1016/j.amjcard.2015.01.538</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-4295-6679</orcidid></addata></record> |
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subjects | Age Aged Arab people Cardiac arrhythmia Cardiomyopathy Cardiovascular Cardiovascular disease Cause of Death - trends Death, Sudden, Cardiac - ethnology Death, Sudden, Cardiac - prevention & control Defibrillators, Implantable Diabetes Disease prevention Diuretics Ethnic Groups Ethnicity Family medical history Female Follow-Up Studies Heart attacks Heart failure Heart Failure - ethnology Heart Failure - therapy Humans Israel - epidemiology Jewish people Male Middle Aged Mortality Multivariate analysis Population Prevalence Prognosis Prospective Studies Survival Rate - trends Variables |
title | Ethnic Differences Among Implantable Cardioverter Defibrillators Recipients in Israel |
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