Prognostic value of 18F-fluorodeoxyglucose uptake in pelvic lymph nodes in patients with cervical cancer treated with definitive chemoradiotherapy

To evaluate the prognostic significance of the maximum standardized uptake (SUVmax) value for pelvic lymph nodes in patients with cervical cancer and its impact on treatment response, disease control, and survival. Ninety-three patients with pelvic or para-aortic metastasis detected by PET/CT and tr...

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Bibliographic Details
Published in:Gynecologic oncology 2015-04, Vol.137 (1), p.40-46
Main Authors: Onal, Cem, Guler, Ozan C., Reyhan, Mehmet, Yapar, Ali Fuat
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Cervical cancer
Chemoradiotherapy
Disease-Free Survival
Female
Fluorodeoxyglucose F18 - pharmacokinetics
Humans
Lymph node metastasis
Lymph Nodes - diagnostic imaging
Lymph Nodes - metabolism
Middle Aged
Multimodal Imaging
Pelvis
Positron emission tomography
Prognosis
Radiopharmaceuticals - pharmacokinetics
Survival Rate
Tomography, X-Ray Computed
Uterine Cervical Neoplasms - diagnostic imaging
Uterine Cervical Neoplasms - metabolism
Uterine Cervical Neoplasms - therapy
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Summary:To evaluate the prognostic significance of the maximum standardized uptake (SUVmax) value for pelvic lymph nodes in patients with cervical cancer and its impact on treatment response, disease control, and survival. Ninety-three patients with pelvic or para-aortic metastasis detected by PET/CT and treated with definitive chemoradiotherapy were evaluated. The impact of pelvic lymph node SUVmax on prognostic factors and treatment outcomes was assessed. The size and SUVmax of pelvic lymph nodes were significantly correlated (r=0.859; p
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2015.01.542